- N Engl J Med 2022; 387:772-774
The risks associated with alcohol consumption are well documented. Requiring new, well-designed warning labels on alcohol containers could provide information to consumers and reduce harm.
- N Engl J Med 2022; 387:672-675
For the one in nine hospitalized U.S. adults who have SUD, hospital-based addiction care has critical health benefits. But most hospitals don’t offer such care.
- N Engl J Med 2022; 387:757-759
Canadian data show that legalization of cannabis for adults has been associated with increased hospitalizations for unintentional cannabis poisoning in children, mostly after legalization of cannabis edibles.
- N Engl J Med 2022; 387:577-579
Health worker burnout, exacerbated by Covid-19, is not only about long hours. It’s about the fundamental disconnect between health workers and the mission to serve that motivates them.
- N Engl J Med 2022; 387:584-585
For professionals who work with children and adolescents, policies like Florida’s “Don’t Say Gay” law have outsized cruelty — even beyond the enormous harm they will do to the young people we serve.
- N Engl J Med 2022; 387:294-297
With policymakers targeting members of sexual and gender minority groups, the health care sector can mitigate resulting harm and advocate for evidence-based policies protecting health and well-being.
- N Engl J Med 2022; 387:102-105
Appropriately, Russia’s war of aggression in Ukraine has prompted a massive humanitarian response — but the assault has intensified and time is running out.
- N Engl J Med 2022; 386:2253-2255
Addressing the overdose epidemic requires eliminating racial and ethnic disparities — along with socioeconomic, gender-based, and geographic disparities — in substance use disorder prevention and care. Prioritizing research that informs policy could help advance equity.
- N Engl J Med 2022; 386:2161-2164
State efforts to prohibit gender-affirming care place physicians’ duties to avoid discrimination, protect privacy, meet standards of care, fulfill reporting requirements, and avoid committing crimes in direct conflict with one another.
- N Engl J Med 2022; 386:2233-2234
A century after “the war to end all wars,” we continue to find our human community divided by conflict and our military service members at the leading edge. The ghostly scars of shell shock, later termed post-traumatic stress disorder (PTSD), have haunted generations of soldiers, as well as civilian survivors...
- N Engl J Med 2022; 386:2169-2177
Microscopic and immunohistochemical examination revealed chronic traumatic encephalopathy in 10 of 225 brains (4.4%) from a military brain bank. The relative risks of CTE were calculated for exposure to blasts, traumatic brain injury, and previous participation in contact sports.
- N Engl J Med 2022; 386:2067-2069
Black girls in America are harmed by intersecting racism and sexism, which manifest in biases, stereotypes, and practices that render them vulnerable to abuse, dehumanization, and death. Our silence about Black girls has clinical consequences throughout their life span.
- N Engl J Med 2022; 386:1967-1969
Not all people who use drugs are interested in recovery support or medications for opioid use disorder. For patients who decline such care, the health care system does next to nothing to reduce the risk of death — but not because nothing can be done.
- N Engl J Med 2022; 386:1965-1967
There is mounting interest among state and local officials in the United States in opening overdose-prevention centers, but there remains one fundamental barrier: the interpretation and enforcement of federal law.
- N Engl J Med 2022; 386:1950-1952
A recent study of mouse models implicates dopaminergic nerve terminals in the amygdala in releasing the brakes on rapid-eye-movement sleep and on cataplexy in a mouse model of narcolepsy. REM sleep is believed to have a role in processing emotional memories and is under investigation in persons with post-traumatic stress...
- N Engl J Med 2022; 386:1581-1583
Although restricting access to nontobacco flavors of e-cigarettes may reduce vaping among adolescents and mitigate associated risks, it could also impede smoking cessation among adults, thereby increasing smoking-attributable mortality. But policy solutions could exist.
- N Engl J Med 2022; 386:1345-1350
The diagnosis of Creutzfeldt–Jakob disease has advanced from detection of characteristic EEG and MRI features to include the detection in CSF of 14-3-3 protein and, with the use of RT-QuIC assays, of abnormally folded prion protein, with close to 100% sensitivity and specificity.
Case 7-2022: A 65-Year-Old Woman with Depression, Recurrent Falls, and Inability to Care for HerselfN Engl J Med 2022; 386:977-986
A 65-year-old woman was admitted with depression, recurrent falls, and difficulty caring for herself. She reported weakness on the left side and had a monoplegic gait, but results of strength testing were normal. She was treated for functional neurologic disorder but then had progressive neurologic decline. A diagnostic test was...